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Spain · national access and guidance

DoxyPEP in Spain

DoxyPEP can be accessed in Spain, but SHAPE's review did not find it reimbursed.

Available, not reimbursed

Last checked 02/11/2026 · This is information only, not advice or a recommendation.

Spanish expert guidance treats DoxyPEP as off-label and individualized for men who have sex with men and transgender women with repeated STIs, not for systematic use; national reimbursement was not confirmed. [Source: https://www.sanidad.gob.es/areas/DCVIHT/ITS/docs/seimc-rc-2024-GEITS-GEMARA-GeSIDA-Posicionamiento-DoxiPEP.pdf]

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Based on public, cited sources and SHAPE's review. Rules and prices change, so please confirm with the national authority or a professional. Found an error? Tell us.